PhD Student Laboratory of Experimental Vascular Medicine

PhD Student Laboratory of Experimental Vascular Medicine

Job description

Project
Elevated plasma triglycerides are an independent risk factor for cardiovascular disease, and are seen in patients suffering from the metabolic syndrome, type 2 diabetes and combined hyperlipidemia. We hypothesize that impaired lipolysis, the first step in TG-rich lipoprotein clearance, is at the basis of this abnormality. Understanding the in vivo regulation of lipolysis will provide handholds for novel strategies to reduce CVD. This project is funded by the Dutch Heart Association.

Tasks
The candidate will work in the Laboratory of Experimental Vascular Medicine. The candidate will perform experimental studies into the molecular steps that underlie lipolysis, including experiments to study the interaction between LPL and GPIHBP1 using plasmon surface resonance (BiaCore) and studies into transcellular LPL transport. The candidate will also help performing in vivo studies directed towards understanding of LPL action in the context of hypertriglyceridemia, including tissue localization in adipose tissue and skeletal muscle in humans and in mouse models of hypertriglyceridemia.

Requirements

We are looking for an enthusiastic PhD student (master in molecular biology, biochemistry or medical biology).
The following techniques will be used:
• Cloning
• BiaCore
• Immune histochemistry
• RT-PCR
• Animal experiments
• ChIP-seq and co-immunoprecipitation

Conditions of employment

Based on a full-time appointment (36 hours per week), compensation will be according to standard salary levels for PhD students (€2086,- gross per month and maximally €2673,- per month in the final year.)

Contract type

Temporary

4 years

Additional information

Additional information about the vacancy can be obtained from:
Geesje M Dallinga-Thie, PhD
Laboratory of Experimental vascular Medicine, Department of Vascular Medicine
Telephone number: +31 (0) 20 566 5158

Applications should include a detailed curriculum vitae and a letter of motivation, and be sent to: M.E.Tromp@amc.uva.nl

5995
Direct link to this job www.academictransfer.com/5995

EURIAS Fellowship (2011-2012): Call for applications scholarships for nurses

EURIAS Fellowship (2011-2012): Call for applications :

Beasiswa Scholarships : EURIAS Fellowship (2011-2012): Call for applications

The European Institutes for Advanced Study (EURIAS) Fellowship Programme is an international researcher mobility programme offering 33 fellowships for the 2011/2012 academic year. It proposes 10-month residencies in one of the 14 participating Institutes: Berlin, Bologna, Brussels, Bucharest, Budapest, Cambridge, Helsinki, Jerusalem, Lyons, Nantes, Paris, Uppsala, Vienna, Wassenaar. The Programme builds on the strong reputation of the Institutes for Advanced Study for promoting the concentrated, self-directed work of excellent researchers within the stimulating environment of a multidisciplinary and international group of fellows.


EURIAS Fellowships are mainly offered in the fields of the humanities and social sciences but may also be granted to scholars in natural and exact sciences, if their proposed research project does not require laboratory facilities. The diversity of the 14 participating IAS —which have agreed on a common selection procedure— offers a wide range of possible research contexts in Europe for worldwide scholars. Applicants select up to three IAS outside their country of nationality or residence as possible host institutions.

The Programme welcomes applications worldwide from promising scholars at an early stage of their careers as well as from established senior researchers.

During their fellowship, EURIAS fellows benefit from the high-quality research environment and working conditions provided by the host Institute. All IAS have agreed on common standards, including the provision of a living allowance (in the range of € 26,000 for a junior fellow and € 38,000 for a senior fellow),accommodation (or a mobility allowance), a research budget, plus coverage of travel expenses.
Application and deadline

Applications are submitted online via www.eurias-fp.eu. You will find detailed information regarding the content of the application, eligibility criteria, selection procedure, etc.

The deadline for application is September 10th 2010. Late applications will not be considered.
Selection procedure

* Scientific assessment by two international referees
* Preselection by EURIAS international and multi-disciplinary Scientific Committee
* Final selection by the IAS academic boards
* Publication of results in December 2010.

For further information on the Programme, please consult EURIAS website

For further information on the IAS and their working conditions: http://www.eurias-fp.eu/institutes

http://www.eurias-fp.eu/